Related Experiment Video

Updated: Apr 15, 2026

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery
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Published on: April 14, 2016

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Pharmacogenetic Testing for Analgesic Adverse Effects: Pediatric Case Series

Renee C B Manworren1, Lauren Jeffries, Ashley Pantaleao

  • 1*Division of Pain and Palliative Medicine, Connecticut Children's Medical Center, Hartford, CT †Department of Pediatrics, University of Connecticut School of Medicine, Farmington §Genetics Research Center, Hartford Hospital, Hartford ‡Center for the Advancement in Managing Pain, University of Connecticut School of Nursing Storrs ∥Genetics Research Center, Hartford Hospital, Genomas Laboratory of Personalized Health Inc, Hartford, CT.

The Clinical Journal of Pain
|March 25, 2015
PubMed
Summary

Pharmacogenetic testing identified genetic variants in CYP2D6, CYP2C19, and CYP2C9 in most pediatric pain patients, impacting analgesic efficacy and safety. This highlights the need for integrating genetic insights into pain management strategies.

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