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Longitudinal In Vivo Imaging of the Cerebrovasculature: Relevance to CNS Diseases
07:47

Longitudinal In Vivo Imaging of the Cerebrovasculature: Relevance to CNS Diseases

Published on: December 6, 2016

7.7K

[Long-term prognosis of children with cerebrovascular disease]

Mana Kurihara, Manabu Yoshihashi, Hiroyuki Fujita

    No to Hattatsu = Brain and Development
    |March 26, 2015
    PubMed

    Insights

    Pediatric cerebrovascular disease (CVD) outcomes vary by stroke type. Hemorrhagic stroke (HS) and ischemic stroke (IS) in children present different causes, affected brain regions, and resulting disabilities, though severe outcomes are rare.

    Area of Science:

    • Neurology
    • Pediatrics
    • Vascular Medicine

    Context:

    • Cerebrovascular disease (CVD) in children is uncommon, with limited data on long-term prognosis.
    • Understanding the differences between hemorrhagic stroke (HS) and ischemic stroke (IS) in pediatric populations is crucial for effective management.

    Purpose:

    • To investigate and compare the prognoses of pediatric hemorrhagic stroke (HS) and ischemic stroke (IS).
    • To analyze the etiologies, affected brain regions, and sequelae in children following HS and IS.

    Summary:

    • This study reviewed 71 pediatric CVD cases (43 HS, 28 IS), analyzing clinical courses and sequelae after at least one year.
    • Etiologies differed: arteriovenous malformation rupture in HS, and traumatic brain injury/surgical complications in IS.
    • Sequelae included physical and mental disabilities, epilepsy, and higher brain dysfunction, with severe outcomes being infrequent.

    Impact:

    • Findings highlight distinct etiological pathways, neurological involvement, and long-term functional outcomes for HS versus IS in children.
    • This research provides valuable insights for pediatric neurologists and healthcare providers managing childhood stroke.
    • The data can inform targeted interventions and improve prognostication for pediatric CVD patients.
    Abstract

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