Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multi-infusion setups in neonatal intensive care unit (NICU) a mass transport evaluation and graphical user interface development.

Scientific reports·2026
Same author

Medium-term outcomes of aortic valve-sparing procedure in trileaflet valve: Longitudinal analysis from the Heart Valve Society Registry.

JTCVS structural and endovascular·2026
Same author

Aortic Growth After Isolated Aortic Valve Repair in Patients With Aortic Regurgitation Without Primary Aneurysm Indication.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery·2026
Same author

Manufacturing 3D aortic root models for in vitro assessment of calcific aortic valve stenosis.

Annals of biomedical engineering·2026
Same author

An Automated Modular Platform for Vascular Graft Assessment via Coronary-like Flow-Induced Stimulation.

Bioengineering (Basel, Switzerland)·2026
Same author

In Vitro Assessment of Coronary Perfusion after Valve-in-Valve Transcatheter Aortic Valve Implantation in a High-Risk Patient-Specific Experimental Model.

Journal of cardiovascular translational research·2026

Related Experiment Video

Updated: Apr 15, 2026

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
13:07

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression

Published on: January 15, 2022

4.7K

Aortic interleaflet triangles reshaping: hydrodynamic, kinematic and morphological effects in in-vitro analysis.

Claudia Romagnoni, Andrea Mangini, Riccardo Vismara

    The Journal of Heart Valve Disease
    |March 26, 2015
    PubMed
    Summary

    Subcommissural triangles reshaping improves leaflet coaptation in the ventriculo-aortic junction. This surgical technique alters hemodynamics and leaflet motion without causing clinically significant issues.

    More Related Videos

    Protocol for Relative Hydrodynamic Assessment of Tri-leaflet Polymer Valves
    11:12

    Protocol for Relative Hydrodynamic Assessment of Tri-leaflet Polymer Valves

    Published on: October 17, 2013

    14.3K
    In vitro Assessment of Aortic Regurgitation Using Four-Dimensional Flow Magnetic Resonance Imaging
    11:16

    In vitro Assessment of Aortic Regurgitation Using Four-Dimensional Flow Magnetic Resonance Imaging

    Published on: February 25, 2022

    4.0K

    Related Experiment Videos

    Last Updated: Apr 15, 2026

    Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
    13:07

    Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression

    Published on: January 15, 2022

    4.7K
    Protocol for Relative Hydrodynamic Assessment of Tri-leaflet Polymer Valves
    11:12

    Protocol for Relative Hydrodynamic Assessment of Tri-leaflet Polymer Valves

    Published on: October 17, 2013

    14.3K
    In vitro Assessment of Aortic Regurgitation Using Four-Dimensional Flow Magnetic Resonance Imaging
    11:16

    In vitro Assessment of Aortic Regurgitation Using Four-Dimensional Flow Magnetic Resonance Imaging

    Published on: February 25, 2022

    4.0K

    Area of Science:

    • Cardiovascular Surgery
    • Biomedical Engineering
    • Cardiac Mechanics

    Background:

    • Subcommissural triangles reshaping is a surgical technique to remodel the ventriculo-aortic junction.
    • The ventriculo-aortic junction's integrity is crucial for proper heart function.
    • Understanding the impact of surgical interventions on cardiac mechanics is vital for improving patient outcomes.

    Purpose of the Study:

    • To evaluate the in-vitro effects of subcommissural triangles reshaping on hemodynamics.
    • To assess the impact of this technique on leaflet kinematics.
    • To analyze the changes in aortic root functional unit morphology after reshaping.

    Main Methods:

    • Utilized 21 porcine aortic roots in a pulsatile mock loop.
    • Performed subcommissural triangles reshaping at 50% of interleaflet triangle height.
    • Recorded hydrodynamic quantities, high-speed digital videos, and echocardiographic images.

    Main Results:

    • Significant increase in leaflet coaptation height and length (p < 0.01).
    • Reduced virtual basal ring and sinus of Valsalva diameters (p < 0.01).
    • Altered leaflet kinematics including reduced maximum opening and opening area (p < 0.01).

    Conclusions:

    • Subcommissural triangles reshaping increases leaflet coaptation by remodeling the ventriculo-aortic junction.
    • The procedure induces hydrodynamic and kinematic changes.
    • Observed alterations were not clinically threatening in acute settings.