Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Oxidation of Phenols to Quinones01:17

Oxidation of Phenols to Quinones

5.4K
In the presence of oxidizing agents, phenols are oxidized to quinones. Quinones can be easily reduced back to phenols using mild reducing agents. The electron-donating hydroxyl group enhances the reactivity of the aromatic ring, enabling oxidation of the ring even in the absence of an α hydrogen.
o-hydroxy phenols are oxidized to o-quinones and p-hydroxy phenols to p-quinones. Such redox reactions involve the transfer of two electrons and two protons. The reversible redox...
5.4K
Electron Transport Chain: Complex III and IV01:43

Electron Transport Chain: Complex III and IV

9.9K
During the electron transport chain, electrons from NADH and FADH2 are first transferred to complexes I and II, respectively. These two complexes then transfer the electrons to ubiquinol, which carries them further to complex III. Complex III passes the electrons across the intermembrane space to Cyt c, which carries them further to complex IV. Complex IV donates electrons to oxygen and reduces it to water. As electrons pass through complexes I, III, and IV, the energy released aids the pumping...
9.9K
Radical Autoxidation01:20

Radical Autoxidation

3.4K
The oxidation of an organic compound in the presence of air or oxygen is called autoxidation. For example, cumene reacts with oxygen to form hydroperoxide. Autoxidation involves initiation, propagation, and termination steps. Many organic compounds are susceptible to autoxidation—especially ethers in the presence of oxygen, which form hydroperoxides. Even though this reaction is slow, old ether bottles contain small amounts of peroxide, which leads to laboratory explosions during ether...
3.4K
Oxidation-Reduction Reactions03:11

Oxidation-Reduction Reactions

79.1K
Oxidation–Reduction Reactions
79.1K
Oxidation and Reduction of Organic Molecules01:19

Oxidation and Reduction of Organic Molecules

10.8K
Energy production within a cell involves many coordinated chemical pathways. Most of these pathways are combinations of oxidation and reduction reactions, which occur at the same time. An oxidation reaction strips an electron from an atom in a compound, and the addition of this electron to another compound is a reduction reaction. Because oxidation and reduction usually occur together, these pairs of reactions are called redox reactions.
The removal of an electron from a molecule, results in a...
10.8K
Oxidation of Alcohols02:37

Oxidation of Alcohols

18.5K
In this lesson, the oxidation of alcohols is discussed in depth. The various reagents used for oxidation of primary and secondary alcohols are detailed, and their mechanism of action is provided.
The process of oxidation in a chemical reaction is observed in any of the three forms:
18.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Catalytic Hydrophosphorylation of Propiolates and Three-Component Phosphorylation of Aldehydes.

The Journal of organic chemistry·2026
Same author

Assessment of levothyroxine therapy adequacy in low-risk differentiated thyroid carcinoma: a multicenter cohort study.

Frontiers in endocrinology·2025
Same author

Implementation of cervical ultrasound and related techniques in endocrinology and nutrition services in Spain. ECOSEEN 2025 study.

Endocrinologia, diabetes y nutricion·2025
Same author

Control of Tetrazine Bioorthogonal Reactivity by Rotaxanation.

Angewandte Chemie (International ed. in English)·2025
Same author

Intraoperative phrenic nerve stimulation to prevent diaphragm fiber weakness during thoracic surgery.

PloS one·2025
Same author

Preoperative use of intra-aortic balloon pump before left ventricular assist device implantation.

JHLT open·2025

Related Experiment Video

Updated: Apr 15, 2026

Monitoring the Reductive and Oxidative Half-Reactions of a Flavin-Dependent Monooxygenase using Stopped-Flow Spectrophotometry
12:08

Monitoring the Reductive and Oxidative Half-Reactions of a Flavin-Dependent Monooxygenase using Stopped-Flow Spectrophotometry

Published on: March 18, 2012

15.8K

Oxidation with air by ascorbate-driven quinone redox cycling.

Gastón Silveira-Dorta1, Diego M Monzón, Fernando P Crisóstomo

  • 1Departamento de Química Orgánica, Instituto Universitario de Bio-Orgánica "Antonio González" (IUBO), Centro de Investigaciones Biomédicas de Canarias (CIBICAN), Universidad de La Laguna, Avda. Astrofísico Fco. Sánchez 2, Apdo. Correos 456, 38200 - La Laguna, S/C. de Tenerife, Spain. rocarril@ull.es.

Chemical Communications (Cambridge, England)
|March 26, 2015
PubMed
Summary

This study introduces a novel, metal-free oxidation method using vitamin C and vitamin K3. This process efficiently converts air into hydrogen peroxide for oxidizing various chemical compounds at room temperature.

More Related Videos

Simultaneous Measurement of Superoxide/Hydrogen Peroxide and NADH Production by Flavin-containing Mitochondrial Dehydrogenases
08:57

Simultaneous Measurement of Superoxide/Hydrogen Peroxide and NADH Production by Flavin-containing Mitochondrial Dehydrogenases

Published on: February 24, 2018

10.6K
Expression and Purification of Nuclease-Free Oxygen Scavenger Protocatechuate 3,4-Dioxygenase
10:14

Expression and Purification of Nuclease-Free Oxygen Scavenger Protocatechuate 3,4-Dioxygenase

Published on: November 8, 2019

6.9K

Related Experiment Videos

Last Updated: Apr 15, 2026

Monitoring the Reductive and Oxidative Half-Reactions of a Flavin-Dependent Monooxygenase using Stopped-Flow Spectrophotometry
12:08

Monitoring the Reductive and Oxidative Half-Reactions of a Flavin-Dependent Monooxygenase using Stopped-Flow Spectrophotometry

Published on: March 18, 2012

15.8K
Simultaneous Measurement of Superoxide/Hydrogen Peroxide and NADH Production by Flavin-containing Mitochondrial Dehydrogenases
08:57

Simultaneous Measurement of Superoxide/Hydrogen Peroxide and NADH Production by Flavin-containing Mitochondrial Dehydrogenases

Published on: February 24, 2018

10.6K
Expression and Purification of Nuclease-Free Oxygen Scavenger Protocatechuate 3,4-Dioxygenase
10:14

Expression and Purification of Nuclease-Free Oxygen Scavenger Protocatechuate 3,4-Dioxygenase

Published on: November 8, 2019

6.9K

Area of Science:

  • Organic Chemistry
  • Green Chemistry
  • Catalysis

Background:

  • Traditional oxidation reactions often rely on transition metals, posing environmental and cost concerns.
  • Developing sustainable and efficient oxidation methods is crucial for modern chemical synthesis.

Purpose of the Study:

  • To establish a transition metal-free oxidation protocol using readily available vitamins.
  • To demonstrate the in situ generation of hydrogen peroxide for oxidative transformations.

Main Methods:

  • Employing ascorbate (vitamin C) and menadione (vitamin K3) as catalysts.
  • Utilizing atmospheric oxygen as the oxidant at room temperature.
  • Applying the generated hydrogen peroxide to oxidize arylboronic acids and other substrates.

Main Results:

  • Achieved efficient, transition metal-free oxidation under ambient conditions.
  • Demonstrated the synergistic action of ascorbate and menadione in generating hydrogen peroxide.
  • Successfully oxidized various arylboronic acids and related chemical moieties.

Conclusions:

  • The vitamin-based system offers a sustainable and effective alternative for oxidation reactions.
  • This method provides a greener approach to chemical synthesis, avoiding hazardous metal catalysts.
  • The in situ generation of hydrogen peroxide is a key feature for facile oxidation processes.