Calvarial ectopic meningothelial meningioma

Roberto Bezerra Vital1, Pedro Tadao Hamamoto Filho2, Renan Luiz Lapate2

  • 1Resident of Neurosurgery at Hospital das Clínicas, UNESP, Botucatu, Brazil.

Abstract

Insights

Ectopic intraosseous meningiomas are rare brain tumors. Surgical removal is the recommended treatment for this unusual neoplasm, offering the best curative option.

Area of Science:

  • Neuro-oncology
  • Neurosurgery
  • Pathology

Background:

  • Meningiomas are the most common benign brain neoplasms.
  • Ectopic meningiomas, particularly intraosseous types, are rare occurrences.
  • Intraosseous meningiomas require differential diagnosis from primary bone tumors like fibrous dysplasia.

Purpose of the Study:

  • To report a rare case of ectopic intraosseous meningioma.
  • To discuss the diagnostic challenges and treatment of intraosseous meningiomas.

Main Methods:

  • A case of a 62-year-old female with a progressive parietal bulge and headaches was analyzed.
  • Surgical resection via parietal craniotomy and immediate cranioplasty were performed.
  • Histopathological examination confirmed an ectopic intradiploic meningioma.

Main Results:

  • The tumor was identified as an ectopic intradiploic meningioma.
  • Histopathology showed positive staining for progesterone receptors and epithelial membrane antigen.
  • No invasion of cortical layers was observed.

Conclusions:

  • Ectopic intraosseous meningiomas are rare neoplasms with limited reported cases.
  • Embryological rests or cellular dedifferentiation are proposed etiological theories.
  • Surgical treatment is considered the optimal curative approach for these tumors.