Calvarial ectopic meningothelial meningioma

Area of Science:

• Neuro-oncology
• Neurosurgery
• Pathology

Background:

• Meningiomas are the most common benign brain neoplasms.
• Ectopic meningiomas, particularly intraosseous types, are rare occurrences.
• Intraosseous meningiomas require differential diagnosis from primary bone tumors like fibrous dysplasia.

Purpose of the Study:

• To report a rare case of ectopic intraosseous meningioma.
• To discuss the diagnostic challenges and treatment of intraosseous meningiomas.

Main Methods:

• A case of a 62-year-old female with a progressive parietal bulge and headaches was analyzed.
• Surgical resection via parietal craniotomy and immediate cranioplasty were performed.
• Histopathological examination confirmed an ectopic intradiploic meningioma.

Main Results:

• The tumor was identified as an ectopic intradiploic meningioma.
• Histopathology showed positive staining for progesterone receptors and epithelial membrane antigen.
• No invasion of cortical layers was observed.

Conclusions:

• Ectopic intraosseous meningiomas are rare neoplasms with limited reported cases.
• Embryological rests or cellular dedifferentiation are proposed etiological theories.
• Surgical treatment is considered the optimal curative approach for these tumors.