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Implantation of Left Ventricular Assist Device (LVAD) in Juvenile Landrace Swine: A LVAD Implantation Model of Pediatric Heart Failure
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Implantation of Left Ventricular Assist Device (LVAD) in Juvenile Landrace Swine: A LVAD Implantation Model of Pediatric Heart Failure

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Readmissions After Continuous Flow Left Ventricular Assist Device Implantation: Differences Observed Between Two

Nicholas A Haglund1, Mary E Davis, Nicole M Tricarico

  • 1From the *Division of Cardiovascular Medicine (Haglund, Keebler), †Department of Cardiac Surgery (Maltais, Davis, Tricarico), Vanderbilt University Medical Center, Nashville, Tennessee.

ASAIO Journal (American Society for Artificial Internal Organs : 1992)
|March 26, 2015
PubMed

Insights

Continuous flow left ventricular assist device recipients experienced frequent readmissions. HeartMate-II recipients had higher readmission rates and more multiple readmissions compared to HeartWare recipients within six months post-implant.

Area of Science:

  • Cardiology
  • Medical Devices
  • Clinical Research

Background:

  • Readmissions are common after continuous flow left ventricular assist device (CF-LVAD) implantation.
  • Understanding readmission patterns is crucial for improving patient outcomes.

Purpose of the Study:

  • To compare the frequency and causes of readmissions between HeartMate-II (HM-II) and HeartWare (HW) CF-LVADs within six months post-implantation.
  • To identify specific clinical profiles associated with readmissions in CF-LVAD patients.

Main Methods:

  • Retrospective assessment of 81 patients receiving HM-II (n=35) or HW (n=46) CF-LVADs as bridge to transplant.
  • Readmissions categorized into cardiac, infection, gastrointestinal bleeding, stroke, pump thrombosis, and miscellaneous profiles.
  • Analysis of readmission rates and etiologies at six months post-implant.

Main Results:

  • Overall readmission rate was higher for HM-II recipients (2.3) versus HW recipients (1.4) at six months (p=0.024).
  • Multiple readmissions (≥2) were more frequent in HM-II recipients (66%) compared to HW recipients (44%) (p=0.047).
  • Arrhythmia and infection were significantly more common reasons for readmission in HM-II recipients.

Conclusions:

  • Significant differences exist in readmission frequency and patterns between HM-II and HW CF-LVADs.
  • HM-II recipients experienced higher rates of overall and multiple readmissions, particularly due to arrhythmias and infections.
  • Device choice may influence early post-implantation readmission profiles in CF-LVAD patients.

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