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Updated: Apr 15, 2026

An In Vitro Bladder Model of Catheter-Associated Urinary Tract Infection
Published on: June 24, 2025
[Unsterile urine in health human--new paradigm in medicine]
Abstract:
The 3-fold urine culture evaluation in healthy women (24) and men (28) was performed. In 100% of cases, various types of multicomponent aerobic-anaerobic microorganism associations were found. Dominant clusters in the urine of women incleded coagulase-negative staphylococci, Corynebacterium sp., Lactobacillus sp., Peptococcus sp., Propionibacterium sp., in men--coagulase negative staphylococci, Corynebacterium sp., Eubacterium sp. For aerobic microorganisms, level of bacteriuria in both groups was 10(2) CFU/ml, for most anaerobes--≥10(3) CFU/ml. Spectrum of microorganisms isolated from the urine was quite wide and variable. In women, number of assiociates in urine ranged from 3 to 10, in men--from 6 to 9, as well as individually--in each subject, the original range of microorganisms was not repeated in any other case.
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