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Updated: Apr 15, 2026

In Vivo Nanovector Delivery of a Heart-specific MicroRNA-sponge
Published on: June 15, 2018
Use of microRNAs as Anti-Atherosclerosis
Hui Wang, Shutong Shen, Qinkao Xuan
1Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing 210029, China. xiangqingkong_nj@163.com.
Abstract:
MicroRNAs are a class of non-coding RNA molecules that have been reported to play a crucial role in cell signaling via post-transcriptional regulation of gene expression. There is increasing evidence showing that this class of RNA is involved in the pathogenesis of cardiovascular diseases, including atherosclerosis. More recently, it has been demonstrated that microRNAs can function to protect against the development of atherosclerosis. The primary goal of this review is to discuss the discovery, mechanism, and therapeutic use of microRNA molecules as atheroprotective agents.
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