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Complete recovery after severe myxoedema coma complicated by status epilepticus
Jesper Fjølner1, Esben Søndergaard2, Ulla Kampmann2
1Department of Anaesthesiology and Intensive Care, Aarhus University Hospital, Aarhus C, Denmark.
Abstract:
We report a case of life-threatening myxoedema presenting with hypothermia, hypotension, bradycardia, pericardial effusion and deep coma. The condition was complicated by prolonged status epilepticus. The optimal treatment strategy has been debated over the years and the literature is briefly reviewed. Treatment with l-thyroxine (LT4) monotherapy without initial loading dose and with no l-triiodothyronine (LT3) treatment was successful with full recovery after hospitalisation for more than a month. Myxoedema coma is a rare, reversible condition with a high mortality and should be considered as a differential diagnosis in medical emergencies.
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