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Updated: Apr 15, 2026

Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
Lifetime risk: childhood obesity and cardiovascular risk
Julian Ayer1, Marietta Charakida2, John E Deanfield2
1The Heart Centre for Children, The Children's Hospital at Westmead, Sydney, Australia Sydney Medical School, University of Sydney, Sydney, Australia.
Insights
Childhood obesity has surged globally, increasing risks for cardiovascular disease. Early life interventions may mitigate long-term cardiovascular risks in children.
Area of Science:
- Pediatrics
- Cardiology
- Public Health
Background:
- Childhood obesity rates have risen dramatically, with a 47% global increase observed between 1980 and 2013.
- This trend raises significant concerns regarding the future public health burden of cardiovascular disease originating in early life.
Purpose of the Study:
- To review evidence on the link between early life obesity and cardiovascular structure/function changes in children.
- To assess the lifetime cardiovascular disease risk associated with childhood obesity.
- To evaluate the impact of childhood lifestyle interventions on mitigating these cardiovascular risks.
Main Methods:
- Systematic literature review and meta-analysis of observational studies.
- Analysis of longitudinal cohort data examining cardiovascular outcomes.
- Evaluation of intervention studies focusing on lifestyle modifications in pediatric populations.
Main Results:
- Obesity in childhood is associated with detrimental alterations in cardiovascular structure and function.
- Children with obesity face an elevated lifetime risk of developing cardiovascular disease.
- Lifestyle interventions show promise in improving cardiovascular health markers in obese children.
Conclusions:
- Addressing childhood obesity is critical for preventing future cardiovascular disease.
- Early detection and intervention are key to mitigating long-term cardiovascular consequences.
- Public health strategies promoting healthy lifestyles in children are essential.
Abstract:
In a recent report, the worldwide prevalence of childhood obesity was estimated to have increased by 47% between 1980 and 2013. As a result, substantial concerns have been raised about the future burden of cardiovascular (CV) disease that could ensue. The purpose of this review is to summarize and interpret (i) the evidence linking early life obesity with adverse changes in CV structure and function in childhood, (ii) the lifetime risk for CV disease resulting from obesity in childhood, and (iii) the potential effects of lifestyle interventions in childhood to ameliorate these risks.
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