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Related Experiment Video

Updated: Apr 15, 2026

Author Spotlight: Advancing Fertility Preservation in Young Female Cancer Patients Through Ovarian Tissue Vitrification and In Vitro Follicular Growth

Author Spotlight: Advancing Fertility Preservation in Young Female Cancer Patients Through Ovarian Tissue Vitrification and In Vitro Follicular Growth

Published on: August 9, 2024

Ovarian tissue freezing: current status.

Jacques Donnez¹, Marie-Madeleine Dolmans

¹aInfertility Research Unit, Société de Recherche pour l'Infertilité (SRI) bGynecology Research Unit, Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain, Brussels, Belgium.

Current Opinion in Obstetrics & Gynecology

|March 27, 2015

Summary

Ovarian tissue freezing offers fertility preservation for young women. This review clarifies live birth rates and risks, reporting a 25% success rate for reimplantation after careful evaluation.

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Last Updated: Apr 15, 2026

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Published on: October 25, 2024

Area of Science:

Reproductive Medicine
Oncology
Gynecology

Background:

Ovarian tissue freezing is a fertility preservation method for young women facing gonadotoxic treatments.
Reimplantation of frozen-thawed ovarian tissue is considered experimental by the American Society for Reproductive Medicine.
Concerns exist regarding the risk of reimplanting malignant cells in cancer survivors.

Purpose of the Study:

To critically evaluate key aspects of ovarian tissue freezing.
To present accurate data on live birth rates and associated risks.
To address discrepancies in reported success rates from previous reviews.

Main Methods:

Comprehensive literature review focusing on ovarian tissue reimplantation outcomes.
Assessment of risks associated with reimplanting malignant cells, categorized by disease.
Analysis of reported live birth rates from published studies.

Main Results:

Nearly 40 live births have been reported following ovarian tissue reimplantation.
The current review establishes a live birth rate of 25% for ovarian tissue reimplantation.
Risks of malignant cell transmission are evaluated based on specific disease types.

Conclusions:

Accurate patient counseling on fertility preservation options, success rates, and risks is crucial.
Ovarian tissue freezing is an important fertility preservation strategy.
This review provides a more accurate picture of ovarian tissue reimplantation success rates.