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Updated: Apr 15, 2026

A Porcine Model of Acute Autologous Pulmonary Embolism
Published on: September 6, 2024
Diagnosing acute pulmonary embolism with computed tomography: imaging update.
Anand Devaraj1, Charlie Sayer, Sarah Sheard
1*Department of Radiology, Royal Brompton Hospital †Department of Radiology, St George's Hospital ‡Department of Radiology, Guy's and St Thomas' Hospitals, London, UK.
Diagnosing acute pulmonary embolism (PE) is challenging. This review covers optimal computed tomography pulmonary angiography (CTPA) use, patient selection, and emerging techniques for accurate PE diagnosis.
Area of Science:
- Radiology
- Diagnostic Imaging
- Cardiopulmonary Medicine
Background:
- Acute pulmonary embolism (PE) presents diagnostic challenges, with high mortality if missed.
- Increasing imaging referrals and decreasing diagnostic yields for PE are significant concerns.
- Computed tomography pulmonary angiography (CTPA) is the primary imaging modality for suspected PE in emergency departments.
Purpose of the Study:
- To review recent literature on optimizing computed tomography pulmonary angiography (CTPA) for diagnosing acute pulmonary embolism (PE).
- To discuss patient selection, image quality, radiation dose, and specific patient subgroups.
- To explore the role of CTPA beyond diagnosis and emerging imaging techniques.
Main Methods:
- Literature review of recent studies on CTPA for pulmonary embolism.
- Analysis of patient selection criteria and imaging protocols.
- Discussion of advanced CT techniques and their applications.
Main Results:
- Key aspects of patient selection for CTPA are highlighted.
- Strategies for optimizing CTPA image quality and minimizing radiation dose are presented.
- The utility of CTPA in specific populations (e.g., pregnant patients) and its role in follow-up are examined.
Conclusions:
- Optimizing CTPA protocols and patient selection are crucial for accurate and efficient PE diagnosis.
- Emerging techniques like dual-energy CT and single-photon emission CT offer potential advancements.
- Radiology plays a pivotal role in the diagnostic pathway for patients with suspected pulmonary embolism.
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