Related Experiment Video
Updated: Apr 15, 2026

Surgical Induction of Endolymphatic Hydrops by Obliteration of the Endolymphatic Duct
Published on: January 22, 2010
Enoxaparin-induced unilateral hemotympanum
Umit Aydin1, M Burak Asik, M Cemal Gokgoz
1Department of Otolaryngology, Head and Neck Surgery, Gulhane Military Medical Academy, Ankara, Turkey.
Hemotympanum is defined as the presence of blood in the middle ear cavity. It is commonly associated with skull fractures. Spontaneous hemotympanum secondary to anticoagulant therapy is extremely rare. Herein, we report the first case of a 51-year-old woman with right spontaneous hemotympanum related to the use of enoxaparin. Complete resolution of signs and symptoms was accomplished by conservative management. Close follow-up is important to assure resolution and reduce long-term sequelae. The use of anticoagulants should be considered in the differential diagnosis of hemotympanum. This is also a good case for clinicians to be mindful about hemorrhagic complications of anticoagulant treatment.
Hemotympanum is defined as the presence of blood in the middle ear cavity. It is commonly associated with skull fractures. Spontaneous hemotympanum secondary to anticoagulant therapy is extremely rare. Herein, we report the first case of a 51-year-old woman with right spontaneous hemotympanum related to the use of enoxaparin. Complete resolution of signs and symptoms was accomplished by conservative management. Close follow-up is important to assure resolution and reduce long-term sequelae. The use of anticoagulants should be considered in the differential diagnosis of hemotympanum. This is also a good case for clinicians to be mindful about hemorrhagic complications of anticoagulant treatment.
Related Concept Videos
Epistaxis
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
Anticoagulant Drugs: Low-Molecular-Weight Heparins

