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Global stability of a multiple delayed viral infection model with general incidence rate and an application to HIV
1Department of Mathematics, Beijing Technology and Business University, Beijing, 100048, China. jyslt@163.com.
Abstract:
In this paper, the dynamical behavior of a viral infection model with general incidence rate and two time delays is studied. By using the Lyapunov functional and LaSalle invariance principle, the global stabilities of the infection-free equilibrium and the endemic equilibrium are obtained. We obtain a threshold of the global stability for the uninfected equilibrium, which means the disease will be under control eventually. These results can be applied to a variety of viral infections of disease that would make it possible to devise optimal treatment strategies. Numerical simulations with application to HIV infection are given to verify the analytical results.
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