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Pearls and pitfalls in diagnosis and management of coats disease
Andrea Grosso1, Marco Pellegrini, Matteo G Cereda
1*Department of Ophthalmology, Torino Eye Hospital and Centre for Macular Research and Allied Diseases, San Mauro, Italy; †Department of Biomedical and Clinical Science "Luigi Sacco", Eye Clinic, Sacco Hospital, University of Milan, Milan, Italy; ‡Department of Ophthalmology, Torino Eye Hospital, Torino, Italy; §Ophthalmic Consultants of Long Island, Division of Retina and Vitreous, Rockville Centre, New York; and ¶Ophthalmic Consultants of Long Island, Division of Retina and Vitreous, Lynbrook, New York.
Purpose:
To review current literature on Coats disease and provide a structured framework for differentiating challenging clinical features in Coats disease patients.
Methods:
We critically reappraise historical and current literature and present clinical methods for developing a thorough differential diagnosis and management strategy for Coats disease.
Results:
Coats disease is a sporadic, usually unilateral condition typically occurring in young males. When untreated, this disorder can lead to total exudative retinal detachment and secondary glaucoma.
Conclusions:
Anti-VEGF agents are currently a treatment option in combination with ablative therapy of telangiectatic vessels. Anti-VEGF agents appear particularly useful for patients with extensive areas of exudative retinal detachment, and are an effective treatment option for total retinal detachment.
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