Expression of the platelet-common acute lymphoblastic leukaemia associated antigen on normal eosinophils

A murine monoclonal antibody (TP82) raised against normal platelets was found to be reactive with eosinophils and common acute lymphoblastic leukaemia (cALL) cells, and some blast cells from patients with non-lymphoid leukaemia. The antibody showed that the platelet-cALL associated antigen (p24) is also expressed on normal eosinophils, and may prove useful for studying the function as well as the differentiation of eosinophils.