Normovolaemic haemodilution using dextran 70 in thoracic surgery

Normovolaemic haemodilution was undertaken in 10 patients requiring elective thoracic surgery. The resultant blood loss, cell loss, use of donor blood and acid-base changes were compared with those in 10 patients undergoing similar procedures who were anaesthetized in the standard manner. Normovolaemic haemodilution reduces the use of donor blood and provides more satisfactory acid-base status than that in controls. The known antithrombotic effect of dextran 70 (Macrodex; Saphar) did not affect the crude clotting time. The technique is a feasible alternative to use of donor blood, especially when difficulties in supply exist or there is a high risk of disease transmission.