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Fatigue Experiences Among OCD Outpatients.

Massimo Pasquini1, Daria Piacentino2, Isabella Berardelli2

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This study found that non-depressed patients with Obsessive-Compulsive Disorder (OCD) experience less physical and mental fatigue compared to those with Panic Disorder (PD). Fatigue is not a prominent symptom in adult OCD patients without depression.

Keywords:
FatigueMental fatigueOCDObsessive–compulsive disorderPanic disorder

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Area of Science:

  • Psychiatry
  • Clinical Psychology
  • Neuroscience

Background:

  • Obsessive-Compulsive Disorder (OCD) significantly impacts patient functioning and quality of life.
  • While psychopathology and neuropsychological deficits are known in OCD, subjective fatigue experiences remain under-researched.
  • Previous studies have not extensively explored general and mental fatigue in non-depressed OCD patients.

Purpose of the Study:

  • To investigate and compare the subjective experiences of physical and mental fatigue in non-depressed outpatients with OCD versus those with Panic Disorder (PD).
  • To determine if fatigue is a prominent symptom in adult patients diagnosed with OCD.
  • To explore the relationship between comorbid Obsessive-Compulsive Personality Disorder (OCPD) and mental fatigue in OCD patients.

Main Methods:

  • A case-control study comparing 50 non-depressed OCD outpatients with 50 PD outpatients.
  • Utilized Structured Clinical Interview for DSM-IV (SCID-I and SCID-II) for diagnosis.
  • Assessed symptom severity with Yale-Brown Obsessive-Compulsive Scale, Hamilton scales, CGI, and GAF.
  • Measured fatigue using the Multidimensional Fatigue Inventory (MFI).

Main Results:

  • Lower odds of physical fatigue were observed in OCD patients compared to PD patients (OR=0.196).
  • Lower odds of mental fatigue were also found in OCD patients compared to PD patients (OR=0.138).
  • OCD patients with comorbid OCPD reported significantly higher scores for mental fatigue.

Conclusions:

  • Fatigue, including mental fatigue, does not appear to be a primary or prominent experience for adult patients with non-depressed OCD.
  • The findings suggest a distinction in fatigue experiences between OCD and PD, with OCD patients reporting less fatigue.
  • Comorbidity with OCPD may be associated with increased mental fatigue in OCD patients.