Male genital lichen sclerosus
Christopher Barry Bunker1, Tang Ngee Shim1
1Department of Dermatology, University College Hospital, London.
Indian Journal of Dermatology
|March 28, 2015
Summary
Male genital lichen sclerosus (MGLSc) is a chronic inflammatory skin condition causing pain and urinary issues. Chronic urinary occlusion by the foreskin is the likely cause, with surgery or steroids as treatments.
Area of Science:
- Dermatology
- Urology
- Oncology
Background:
- Male genital lichen sclerosus (MGLSc) is a chronic inflammatory skin condition.
- It can lead to painful intercourse and urinary complications.
- A significant concern is the risk of developing penile squamous cell carcinoma (SCC).
Purpose of the Study:
- To explore the etiopathogenesis of MGLSc.
- To identify the most probable cause of MGLSc.
- To outline current and surgical treatment options for MGLSc.
Main Methods:
- Review of existing evidence on MGLSc.
- Analysis of implicated genetic, autoimmune, and infective factors.
- Evaluation of the role of urinary occlusion in MGLSc pathogenesis.
Main Results:
- The exact cause of MGLSc is debated, with various factors implicated.
- Chronic exposure to urinary occlusion by the foreskin is the most likely pathomechanism.
- Topical ultrapotent corticosteroids are the primary treatment.
Conclusions:
- MGLSc requires effective management due to potential complications.
- Urinary occlusion is a key factor in MGLSc development.
- Surgery is reserved for refractory cases or specific complications like SCC.
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