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Evaluating factors associated with uncontrolled hypertension: Isfahan cohort study, Iran

Alireza Khosravi1, Behrouz Pourheidar2, Hamidreza Roohafza3

  • 1Associate Professor, Interventional Cardiology Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.

ARYA Atherosclerosis
|March 28, 2015
PubMed

Insights

Men, salty food consumption, and medication non-adherence are linked to uncontrolled hypertension (HTN). Addressing these factors is crucial for managing blood pressure and reducing cardiovascular risks.

Area of Science:

  • Cardiology
  • Public Health
  • Epidemiology

Background:

  • Hypertension (HTN) is a major risk factor for cardiovascular disease.
  • High prevalence of HTN in Iran necessitates understanding factors affecting blood pressure control.
  • This study investigates socio-demographic and clinical variables associated with uncontrolled HTN in an Iranian cohort.

Purpose of the Study:

  • To identify key factors contributing to the failure of achieving blood pressure control in hypertensive individuals.
  • To examine the association between socio-demographic characteristics, clinical data, and lifestyle behaviors with uncontrolled HTN.
  • To inform targeted interventions for improved hypertension management in the Iranian population.

Main Methods:

  • Retrospective cohort study within the Isfahan cohort study, including adults aged 35+ with confirmed HTN.
  • Data collected via questionnaires on socio-demographic, clinical, and lifestyle factors by trained nurses.
  • Uncontrolled HTN defined as systolic/diastolic blood pressure > 140/90 mmHg, with or without medication.

Main Results:

  • Men exhibited a significantly higher prevalence of uncontrolled HTN compared to women in both 2001 and 2007 (P < 0.001).
  • Being male was strongly associated with uncontrolled HTN (OR = 2.31 in 2001, OR = 2.38 in 2007).
  • Increased consumption of salty foods (OR = 1.73) and being naive to monotherapy (OR = 0.14) were associated with uncontrolled blood pressure.

Conclusions:

  • Uncontrolled HTN is associated with male sex, marital status, diabetes, high salt intake, and medication adherence.
  • Identifying and assessing these risk factors is essential for aggressive HTN management.
  • Effective management aims to reduce the excessive risk of cardiovascular events stemming from uncontrolled HTN.
Abstract

Keywords:
HypertensionPrevalenceRisk FactorsUncontrolled

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