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A simple and efficient method for the preparation of 5-hydroxy-3-acyltetramic acids
Johanna Trenner1, Evgeny V Prusov1
1Department of Medicinal Chemistry, Helmholtz Centre for Infection Research, Inhoffenstr. 7, 38124 Braunschweig, Germany.
Beilstein Journal of Organic Chemistry
|March 28, 2015
Abstract:
Oxidation of the bisenolates of 3-acyltetramic acid to the corresponding 5-hydroxylated compounds using molecular oxygen is reported. The deprotection of the resulting compounds was also achieved.