Related Experiment Video
Updated: Apr 15, 2026

An In Vivo Mouse Model of Total Intravenous Anesthesia During Cancer Resection Surgery
Published on: June 8, 2021
Anesthesia management of a 20-month-old patient with giant unilateral wilms tumor
Nune Matinyan1, Alexander Saltanov1, Leonid Martynov1
1N. N. Blokhin Cancer Research Center, Pediatric Oncology and Hematology Research Institute, Moscow 115478, Russia.
Abstract:
Wilms tumour (WT) (or nephroblastoma) is one of the most common malignant kidney tumors in children. On subsequent stages clinically it is often characterized by abdominal hypertension syndrome, which, in turn, leads to development of respiratory insufficiency. Other symptoms comprise renal deficiency, hypertension, and abnormalities of hemostasis and hemogram. Treatment includes rounds of preoperative chemotherapy and subsequent surgery. We report a case of perioperative management for nephrectomy in 20-month-old patient with a giant unilateral WT. The complexity of anesthesia was determined by the size of tumor, increased intra-abdominal pressure, respiratory deficiency, and hypercoagulation.

