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Updated: Apr 15, 2026

Control of Eating Behavior Using a Novel Feedback System
Published on: May 8, 2018
Neural control of energy balance: translating circuits to therapies
Laurent Gautron1, Joel K Elmquist2, Kevin W Williams3
1Division of Hypothalamic Research, Department of Internal Medicine, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390-9077, USA.
Abstract:
Recent insights into the neural circuits controlling energy balance and glucose homeostasis have rekindled the hope for development of novel treatments for obesity and diabetes. However, many therapies contribute relatively modest beneficial gains with accompanying side effects, and the mechanisms of action for other interventions remain undefined. This Review summarizes current knowledge linking the neural circuits regulating energy and glucose balance with current and potential pharmacotherapeutic and surgical interventions for the treatment of obesity and diabetes.
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