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Cell-matrix's Response to Mechanical Forces

Cell-matrix's Response to Mechanical Forces

In animal cells, the extracellular matrix allows cells within tissues to withstand external stresses and transmits signals from the outside of the cell to the inside. The extracellular matrix is extensive, and its composition varies between different types of tissues. For example, the reticular fibers and ground substance make up the ECM in loose connective tissue, while collagen and bone minerals make up the ECM of bone tissue.
Anchoring junctions mechanically attach a cell to the...

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Related Experiment Video

Updated: Apr 15, 2026

Control of Cell Adhesion using Hydrogel Patterning Techniques for Applications in Traction Force Microscopy

Control of Cell Adhesion using Hydrogel Patterning Techniques for Applications in Traction Force Microscopy

Published on: January 29, 2022

Receptor clustering control and associated force sensing by surface patterning: when force matters

Elisabetta Ada Cavalcanti-Adam¹, Joachim P Spatz

¹Max Planck Institute for Intelligent Systems, Department of New Materials & Biosystems, Heisenbergstr. 3, D-70569 Stuttgart, Germany.

Nanomedicine (London, England)

|March 31, 2015

Summary

No abstract available in PubMed .

Keywords:

biointerfaces extracellular matrix integrins nanopatterns receptor clustering tension sensor

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