Related Experiment Video
Updated: Apr 15, 2026
06:59
A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
Published on: November 9, 2016
31.6K
[Subcutaneous drug administration in palliative care]
Carmen Matoses Chirivella1, Francisco José Rodríguez Lucena2, Gregorio Sanz Tamargo3
1Servicio de Farmacia. Hospital General Universitario de Elche. Alicante. España.. matoses_car@gva.es.
Summary
This guide provides essential information for healthcare staff on administering subcutaneous medications to palliative care patients. It offers recommendations for 65 drugs, aiding safe and effective subcutaneous route management.
Area of Science:
- Palliative Care Medicine
- Pharmacology
- Clinical Pharmacy
Background:
- Subcutaneous drug administration is crucial in palliative care for symptom management.
- Limited comprehensive guidelines exist for healthcare staff regarding subcutaneous drug use in this population.
- Home-based palliative care necessitates accessible and reliable information on drug administration routes.
Purpose of the Study:
- To develop a comprehensive guide for healthcare staff on subcutaneous drug administration in palliative care.
- To compile and synthesize available literature on the subcutaneous route for commonly used palliative care medications.
- To provide evidence-based recommendations for safe and effective subcutaneous drug administration in home-based palliative care settings.
Main Methods:
- Systematic literature review of manufacturer technical reports and scientific publications.
- Database searches conducted on PubMed and Micromedex for relevant drug information.
- Development of a summary table and guide based on reviewed drug administration data.
Main Results:
- A review of 65 drugs was conducted to assess their suitability for subcutaneous administration.
- The guide provides recommendations differentiating between drugs with established subcutaneous administration and those contraindicated.
- Information on subcutaneous administration was found to be lacking for some drugs from manufacturer data.
Conclusions:
- The developed guide facilitates the management of the subcutaneous route for frequently used palliative care medications.
- Despite data limitations from manufacturers, this resource supports healthcare staff in utilizing the subcutaneous route effectively.
- The guide aims to improve the quality of care for palliative care patients by optimizing medication administration.
Related Concept Videos
01:22Drug Delivery: Miscellaneous Routes
1.1K
Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection, and rectal administration provide localized effects with reduced toxicity.
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
1.1K
01:29Drug Delivery: Parenteral Route
2.7K
The parenteral route is a critical method of drug administration. It delivers compounds directly into the systemic circulation and bypasses the gastrointestinal tract. This approach is particularly advantageous for drugs that exhibit poor absorption or instability when administered orally.
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
2.7K
01:25Routes of Drug Administration: Parenteral
3.9K
The administration of drugs via parenteral routes allows for direct drug introduction into the systemic circulation, resulting in high bioavailability because the medication bypasses the harsh conditions of the gastrointestinal tract and hepatic metabolism.
The intravenous route (IV) of drug administration can be further categorized into two types. The bolus injection administers the entire dose rapidly, while an intravenous infusion slowly delivers smaller doses steadily.
The IV route is often...
The intravenous route (IV) of drug administration can be further categorized into two types. The bolus injection administers the entire dose rapidly, while an intravenous infusion slowly delivers smaller doses steadily.
The IV route is often...
3.9K
01:22Routes of Drug Administration: Overview
11.9K
Drug administration involves delivering drugs to the body through various routes, such as enteral, parenteral, and topical.
Enteral administration refers to drugs absorbed through the gastrointestinal tract. They can be swallowed (perorally), placed under the tongue (sublingually), or on the inner lining of the cheeks (buccally). Perorally administered drugs take time to be absorbed and have a slower onset of action. The rectal route is another form of enteral administration, which allows for...
Enteral administration refers to drugs absorbed through the gastrointestinal tract. They can be swallowed (perorally), placed under the tongue (sublingually), or on the inner lining of the cheeks (buccally). Perorally administered drugs take time to be absorbed and have a slower onset of action. The rectal route is another form of enteral administration, which allows for...
11.9K
01:18Additional Routes of Drug Administration
6.2K
Choosing the appropriate route of drug administration is significantly influenced by two key factors: the therapeutic objectives and the inherent properties of the drug being used.
Administering drugs via inhalation allows for the direct delivery of gaseous, volatile substances or droplets to different parts of the respiratory tract. One of the advantages of the inhalation route is the rapid absorption of drugs into the circulatory system, which is possible because of the large surface area of...
Administering drugs via inhalation allows for the direct delivery of gaseous, volatile substances or droplets to different parts of the respiratory tract. One of the advantages of the inhalation route is the rapid absorption of drugs into the circulatory system, which is possible because of the large surface area of...
6.2K
01:16Drug Delivery: Overview
1.2K
The selection of a drug's delivery route depends upon its physicochemical properties, including lipid or water solubility and ionization, as well as the therapeutic requirement, such as immediate or sustained effect. These routes can be divided into three primary categories: enteral, parenteral, and topical.
Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the...
Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the...
1.2K