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Updated: Apr 15, 2026

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
Coronary CT angiography for chest pain in pseudoxanthoma elasticum and cardiac intervention management
Carma Karam1, Gilles Soulat2, Dominique P Germain3
1Cardiology Department, Ambroise Paré Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Centre de référence des Maladies Cardiaques Héréditaires, University of Versailles-Saint Quentin en Yvelines, UMR-EpReC, 9, Avenue Charles de Gaulle, Boulogne-Billancourt 92100, France.
Insights
A rare cause of severe coronary artery disease was identified in a young woman lacking typical cardiovascular risk factors. Cardiac CT imaging was crucial for diagnosis and guiding cardiac intervention.
Area of Science:
- Cardiology
- Radiology
- Medical Imaging
Background:
- Severe coronary artery disease (CAD) typically affects older individuals with cardiovascular risk factors.
- Rare etiologies of CAD in young, otherwise healthy individuals present diagnostic challenges.
Observation:
- A young woman presented with severe coronary artery disease.
- She had no traditional cardiovascular risk factors such as hypertension, diabetes, or hyperlipidemia.
Findings:
- Cardiac computed tomography (CT) was instrumental in diagnosing the underlying rare cause of CAD.
- CT facilitated the management strategy, including necessary coronary intervention.
Implications:
- This case highlights the importance of considering rare causes of CAD in young patients.
- Cardiac CT is a valuable tool for the diagnosis and management of complex coronary artery disease.
- Early diagnosis and intervention can improve outcomes in young patients with severe CAD.
Abstract:
We describe the case of a rare cause of severe coronary artery disease in a young woman without cardiovascular risk factors. Cardiac CT played an important role in diagnosis and cardiac management including coronary intervention.
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