[Uveal effusion induced by escitalopram]

Area of Science:

• Ophthalmology
• Pharmacology
• Internal Medicine

Background:

• Drug-induced uveal effusion syndrome is a rare condition.
• Secondary angle closure glaucoma can be a complication of uveal effusion.
• Antidepressants, such as escitalopram, can rarely trigger ocular side effects.

Observation:

• A 73-year-old woman on escitalopram for depression experienced acute secondary angle closure glaucoma.
• The ocular event occurred after a dose duplication of escitalopram.
• The patient presented with symptoms of uveal effusion syndrome.

Findings:

• Discontinuation of escitalopram led to favorable evolution of the glaucoma.
• The patient's condition improved with topical hypotensive therapy and oral prednisone.
• This case highlights the potential for escitalopram to induce uveal effusion and secondary angle closure glaucoma.

Implications:

• Early recognition of drug-induced uveal effusion syndrome is crucial.
• Discontinuation of the causative medication is key to managing this condition.
• Ophthalmologists and psychiatrists should be aware of this rare but serious adverse drug reaction.