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Related Concept Videos

Neurulation01:30

Neurulation

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Neurulation is the embryological process which forms the precursors of the central nervous system and occurs after gastrulation has established the three primary cell layers of the embryo: ectoderm, mesoderm, and endoderm. In humans, the majority of this system is formed via primary neurulation, in which the central portion of the ectoderm—originally appearing as a flat sheet of cells—folds upwards and inwards, sealing off to form a hollow neural tube. As development proceeds, the...
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Nervous Tissue: Glial Cells01:31

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Glia, or neuroglia, are vital support cells that assist neurons in their functions. The term "glia" originates from the Greek word for "glue," reflecting their role in holding the nervous system together. These cells can be categorized into six types: four in the central nervous system (CNS) and two in the peripheral nervous system (PNS).
The CNS glial cell includes the astrocytes, the oligodendrocytes, the microglia, and the ependymal cells.
Astrocytes are star-shaped glial...
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Related Experiment Video

Updated: Apr 15, 2026

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
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Multiple calcifying pseudoneoplasms of the neuraxis.

Molly Hubbard1, Rabia Qaiser1, H Brent Clark2

  • 1Department of Neurosurgery, University of Minnesota, Minneapolis, Minnesota, USA.

Neuropathology : Official Journal of the Japanese Society of Neuropathology
|March 31, 2015
PubMed
Summary
This summary is machine-generated.

Calcified pseudoneoplasms of the neuraxis (CAPNON) are rare brain and spine lesions. This case report details the first instance of separate bilateral CAPNON, diagnosed eight years apart in a single patient.

Area of Science:

  • Neuro-oncology
  • Pathology
  • Radiology

Background:

  • Calcified pseudoneoplasms of the neuraxis (CAPNON) represent a rare diagnostic challenge.
Keywords:
CAPNONcalcificationmultiplepseudotumorseizures

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  • These fibro-osseous lesions occur intra-cranially and within the spine, frequently at the skull base.
  • Existing literature documents approximately 46 cases of cerebral and spinal CAPNON.