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Identification of SUMO E3 ligase-specific substrates using the HuProt human proteome microarray.

Eric Cox1, Ijeoma Uzoma, Catherine Guzzo

  • 1Biochemistry, Cellular and Molecular Biology Graduate Program, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Methods in Molecular Biology (Clifton, N.J.)
|March 31, 2015
PubMed
Summary

Researchers developed a human proteome array (HuProt) to identify novel SUMO E3 ligase substrates. This systems biology tool screens thousands of proteins, advancing our understanding of SUMOylation and E3 ligase specificity.

Failed At:

2026-06-19T13:37:17.810809+00:00

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