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Korean studies on blood stasis: an overview
Bongki Park1, Sooseong You1, Jeeyoun Jung1
1Medical Research Division, Korea Institute of Oriental Medicine, Daejeon 305-811, Republic of Korea.
Korean medicine research on blood stasis, a concept of stagnant blood, reveals its link to circulation disorders. Studies show herbs activating blood circulation are effective for conditions like traumatic injury and coagulopathy.
Area of Science:
- Korean Medicine
- Pathophysiology
- Herbal Medicine Research
Background:
- Blood stasis is a key pathological concept in Korean medicine, often described as stagnant blood within the body.
- Understanding blood stasis is crucial for developing effective treatments within traditional Korean medicine frameworks.
Purpose of the Study:
- To systematically analyze Korean research on the concept and applications of blood stasis.
- To identify prevalent themes, methodologies, and therapeutic agents investigated in blood stasis studies.
Main Methods:
- A comprehensive literature search was conducted across eight electronic databases up to September 2014.
- Included studies encompassed reviews, clinical trials, and preclinical research focusing on blood stasis.
- Excluded were articles not mentioning or explaining blood stasis.
Main Results:
- A total of 211 studies were included: 19 reviews, 52 clinical, and 140 preclinical.
- "Stagnant blood within the body" was the most common description.
- Traumatic injury (clinical) and coagulopathy (preclinical) were the most studied conditions.
- Hyeolbuchukeo-tang and Angelicae Gigantis Radix were the most frequently used formula and herb, respectively.
Conclusions:
- Blood stasis is primarily recognized as a circulatory disorder in Korean medicine research.
- Evidence suggests the efficacy of blood-activating herbs for conditions like traumatic injury and coagulopathy.
- Further investigation into the pathological mechanisms and diverse disease associations of blood stasis is warranted.
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