Related Experiment Video
Updated: Apr 15, 2026

Surgical Placement of Catheters for Long-term Cardiovascular Exercise Testing in Swine
Published on: February 9, 2016
Physiologic and pathophysiologic changes in the right heart in highly trained athletes
A D'Andrea1, A La Gerche, E Golia
1Second University of Naples, Monaldi Hospital, Via M. Schipa 44, 80122, Naples, Italy, antonellodandrea@libero.it.
Highly trained athletes experience significant right heart adaptations to exercise. However, this can lead to exercise-induced cardiomyopathy and arrhythmias, necessitating further research into these cardiac changes.
Area of Science:
- Cardiology
- Sports Medicine
- Physiology
Background:
- Exercise induces hemodynamic changes, prompting cardiac adaptations.
- Athlete's heart initially focused on left heart changes; right heart adaptations are now recognized.
- Understanding cardiac adaptations is crucial to differentiate from pathological conditions.
Purpose of the Study:
- To review current knowledge on physiologic and pathophysiologic changes in the right heart of highly trained athletes.
- To highlight the structural and functional adaptations of the right heart due to intense training.
- To discuss the potential for exercise-induced cardiac damage and arrhythmias.
Main Methods:
- Literature review of studies on athlete's heart and right ventricular adaptations.
- Analysis of research on exercise-induced cardiac remodeling and potential damage.
- Synthesis of evidence regarding the interplay between left and right heart adaptations.
Main Results:
- Significant structural and functional adaptations occur in the right heart of athletes.
- These adaptations can overlap with pathological changes, complicating diagnosis.
- Evidence suggests acute and chronic right heart damage may occur, increasing arrhythmia risk.
Conclusions:
- The right heart undergoes substantial changes in response to intense exercise.
- Exercise-induced cardiomyopathy, particularly affecting the right heart, is a growing concern.
- Further investigation is needed to understand the mechanisms and clinical implications of these right heart adaptations.
Related Concept Videos
Exercise and Cardiac Output
Sustained exercise increases the muscles' oxygen demand, which can be...
Exercise and Cardiovascular Response
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Heart Failure II: Pathophysiology
Pathophysiology of Cardiac Performance
Pathophysiology of Heart Failure
Mitral Regurgitation I: Introduction

