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Related Concept Videos

Brain Imaging01:14

Brain Imaging

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Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
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Brain/MINDS: brain-mapping project in Japan.

Hideyuki Okano1, Atsushi Miyawaki2, Kiyoto Kasai3

  • 1Laboratory for Marmoset Neural Architecture, Brain Science Institute RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan Department of Physiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 160-8582, Japan hidokano@brain.riken.jp hidokano@a2.keio.jp.

Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
|April 1, 2015
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Summary

Japan

Keywords:
brain mapping by integrated neurotechnologies for disease studiesneuropsychiatric and neurodegenerative diseasesoptogeneticssuper-resolution microscopytissue clearingtransgenic non-human primates

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Area of Science:

  • Neuroscience
  • Neurotechnology
  • Primate Research

Background:

  • Global interest in brain mapping is growing.
  • Japan launched the Brain Mapping by Integrated Neurotechnologies for Disease Studies (Brain/MINDS) project in 2014.
  • The RIKEN Brain Science Institute leads the Brain/MINDS initiative.

Purpose of the Study:

  • To map the structure and function of neuronal circuits in the common marmoset brain.
  • To develop advanced neurotechnologies for comprehensive brain mapping.
  • To advance human brain mapping and clinical research for neurological and psychiatric disorders.

Main Methods:

  • Utilizing the common marmoset (Callithrix jacchus) as a non-human primate model.
  • Integrating structural and functional mapping of the marmoset brain.
  • Developing and applying innovative neurotechnologies for brain mapping.

Main Results:

  • Focus on identifying neuronal circuits underlying neurological and psychiatric disorders.
  • Understanding the developmental aspects of these disorders through integrated research.
  • Advancing the understanding of the human brain's complexity.

Conclusions:

  • The Brain/MINDS project aims to unravel brain complexity using integrated neurotechnologies.
  • Identifying disease-related neuronal circuits is a key objective.
  • Bridging non-human primate research with human brain mapping and clinical applications.