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Tissue Transplantation

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
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Related Experiment Video

Updated: Apr 15, 2026

Engineered Vascularized Muscle Flap

Engineered Vascularized Muscle Flap

Published on: January 11, 2016

Free perivascular tissue flap transfer.

Ken Matsuda¹, Tateki Kubo², Megumi Fukai²

¹Department of Plastic and Reconstructive Surgery, Niigata University Graduate School of Medicine, Niigata, Japan.

Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS

|April 1, 2015

Summary

This summary is machine-generated.

A novel free vascularized perivascular tissue flap offers an effective solution for soft tissue reconstruction, overcoming limitations of traditional methods. This versatile flap is suitable for various defects and can incorporate bone or cartilage.

Keywords:

Anterolateral thigh flap Fascial flap Free flap Perifascial areolar tissue Soft tissue defect

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Area of Science:

Plastic Surgery
Reconstructive Surgery
Vascular Surgery

Background:

Local flaps and composite grafts are standard for small soft tissue defects.
These methods have limitations including large dissection areas, long incisions, and need for well-vascularized beds.

Observation:

A free vascularized perivascular tissue flap, based on the lateral femoral circumflex artery, was utilized for reconstruction.
This technique was applied to seven patients with soft tissue defects in the head/neck and lower limb.

Findings:

The flap was easily elevated, adaptable in volume, and did not require precise preoperative design.
It demonstrated a rich vascular supply, enabling combined transfer of soft tissue with bone or cartilage.
The flap successfully treated chronic wounds with compromised blood supply.

Implications:

This technique provides a versatile and effective alternative for soft tissue reconstruction, particularly for challenging defects.
It expands reconstructive options for complex wounds, including those involving bone or cartilage and those with poor vascularity.