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Updated: Apr 15, 2026

Biological Compatibility Profile on Biomaterials for Bone Regeneration
Published on: November 16, 2018
Calcium phosphate barrier for augmentation of bone in noncontained periodontal osseous defects: a novel approach
Aditi Chopra1, Karthik Sivaraman2, Tarun K Awataramaney3
1Master, Department of Periodontology, Manipal College of Dental Sciences Manipal University, 203, Angels Court Behind KMC Library Vidyaratna Nagar Manipal-576104, Karnataka, India, Phone: +91-9739863908,
Aim:
The aim of this technique is to augment bone in non-contained osseous deformities using a unique self-sustaining calcium phosphate barrier.
Introduction:
Bone has the inherent ability to regenerate completely if it is provided with a fracture space or an undisturbed enclosed scaffold. A secluded environment is essential as it provides a secured, sterile and stable wound system that regenerates lost bone by a process of osteopromotion. Reconstructive techniques using bone grafts and barrier membranes utilize this principle for augmentation of deficient bony sites by providing a closed environment that promotes clot stability, graft retention, and facilitates correct cell repopulation. However, in noncontained bone defects like one walled infrabony periodontal defect or sites with horizontal bone loss, regeneration of bone still remains an unrealistic situation since osseous topography at such sites does not favor membrane stability or bone grafts retention. This case report presents a promising technique to augment bone in areas with horizontal loss.
Technique:
Augmentation of bone in the interdental area with horizontal bone loss was accomplished by building a contained defect using a unique self sustaining calcium phosphate cement formulation. The calcium phosphate barrier stimulates the lost cortical plates and promotes graft retention and clot stability. At 6 months, there was a significant bone fill and trabecular formation in the interdental area and reduction in tooth mobility.
Conclusion:
This promising technique could prove to be a good alternative to the conventional approaches for treating osseous deformities.
Clinical Significance:
Calcium phosphate is a promising barrier graft for repair of noncontained periodontal osseous defect. This technique cues both the clinicians and manufacturers to develop moldable tissue engineered constructs for osseous repair.
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