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Nasal congestion during pregnancy.

M Bende¹, M Hallgårde, U Sjögren

¹Department of Otorhinolaryngology, Central Hospital, Skövde, Sweden.

Clinical Otolaryngology and Allied Sciences

|October 1, 1989

Summary

Pregnancy rhinitis is common, but its cause remains unclear. This study found lower oxytocin levels in pregnant women with nasal congestion, suggesting a potential hormonal link.

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Area of Science:

Obstetrics and Gynecology
Otolaryngology
Reproductive Endocrinology

Background:

Nasal congestion during pregnancy, often termed 'pregnancy rhinitis,' affects many expectant mothers.
The exact physiological mechanisms driving nasal congestion in pregnancy are not well understood.
Hormonal fluctuations during pregnancy are known to influence various bodily functions.

Purpose of the Study:

To investigate potential hormonal differences in pregnant women experiencing nasal congestion.
To explore the relationship between serum hormone levels and the presence of nasal congestion during gestation.
To examine associated pregnancy symptoms in relation to nasal congestion.

Main Methods:

Recruitment of pregnant women with and without objectively verified nasal congestion (using rhinomanometry).
Measurement of serum levels for key hormones: oestradiol, progesterone, oxytocin, and vasoactive intestinal peptide (VIP).
Comparison of hormone levels and reported symptoms (urinary incontinence, constipation, heartburn) between the congested and non-congested groups.

Main Results:

No significant differences in serum oestradiol, progesterone, or VIP levels were observed between groups.
Pregnant women with nasal congestion exhibited significantly lower serum oxytocin levels compared to the control group.
No significant differences in the prevalence of urinary incontinence, constipation, or heartburn were found between the groups.

Conclusions:

Lower oxytocin levels may play a role in the pathophysiology of nasal congestion during pregnancy.
The findings suggest a potential hormonal influence on pregnancy-related nasal congestion.
Further research is warranted to elucidate the precise mechanisms linking oxytocin and nasal congestion in pregnancy.

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