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Published on: February 4, 2017
Tetrazolium compounds: synthesis and applications in medicine
Cheng-Xi Wei1, Ming Bian2, Guo-Hua Gong3,4
1Medicinal Chemistry and Pharmacology Institute, Inner Mongolia University for the Nationalities, Tongliao 028000, Inner Mongolia, China. weichengxi1224@163.com.
Abstract:
Tetrazoles represent a class of five-membered heterocyclic compounds with polynitrogen electron-rich planar structural features. This special structure makes tetrazole derivatives useful drugs, explosives, and other functional materials with a wide range of applications in many fields of medicine, agriculture, material science, etc. Based on our research works on azoles and other references in recent years, this review covers reported work on the synthesis and biological activities of tetrazole derivatives.
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