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Cardiac status of persons qualified for living kidney donation--single-center experience
Insights
Many living kidney donor candidates have cardiovascular disease risk factors. Cardiologic issues frequently disqualify potential donors, highlighting the need for thorough pre-donation screening.
Area of Science:
- Nephrology
- Cardiology
- Transplant Surgery
Background:
- Living kidney donation is crucial for patients with end-stage renal disease.
- Potential donors may have underlying medical conditions, including cardiovascular risks.
- Pre-donation screening is essential to ensure donor safety and long-term health.
Purpose of the Study:
- To assess the cardiological status of individuals evaluated as living kidney donors.
- To identify cardiovascular risk factors and disorders in potential kidney donors.
- To determine the prevalence of cardiological disqualifications among living kidney donor candidates.
Main Methods:
- Analysis of data from 109 potential living kidney donors (age 25-70).
- Inclusion of clinical examinations, biochemical tests, and extended diagnostics.
- Registration of coronary artery disease risk factors and performance of ambulatory blood pressure monitoring and exercise tests.
Main Results:
- Only 46% of candidates were qualified for donation; 40% had at least one risk factor.
- Masked hypertension was detected in 6 individuals; 3 exercise tests were inconclusive or positive.
- Cardiological reasons led to disqualification in 23.8% of candidates, including abdominal aneurysms and atrial fibrillation.
Conclusions:
- Living kidney donor candidates frequently present with cardiovascular disease risk factors.
- Cardiovascular issues represent a significant cause for disqualification in potential living kidney donors.
- Comprehensive cardiological evaluation is vital for living kidney donor assessment.
Unlabelled:
Some of living kidney donors have medical conditions associated with future risk of cardiovascular diseases. It seems justified to identify risk factors and cardiological disorders prior to the donation.
Aim:
To determine the cardiological status of persons qualified as a living kidney donor.
Material And Methods:
We analyzed the data of 109 potential living kidney donors, aged 25-70 (mean 45.7 ± 10.9) years. They underwent clinical and biochemical examination. In some of them extended diagnostics was performed. The presence of risk factors of coronary artery disease were registered.
Results:
Only 46 (42%) persons were qualified for kidney donation. As many as 40 of them had 21 risk factor. In 75 (68.8%) patients without hypertension, 24-hours ambulatory blood pressure monitoring was done. The masked hypertension was found in 6 persons. In 22 candidates aged > 50 years the exercise test was performed (positive or inconclusive in 3 persons). Coronarography was done in 5 individuals (in no any significant atherosclerotic lesions were found). 63 (58%) person were disqualified. In 15 (23.8%) person the reasons were cardiological. In 2 patient the abdominal aneurysms were found. Both men smoked and had severe dyslipidaemias. In 3rd patient we observed persistent atrial fibrillation. The next 2 men had the peripheral occlusive arterial disease. In 9 patients ≥ 2 risk factors and in the last one morbid obesity were present.
Conclusion:
In Poland candidates for living kidney donation have very often risk factors of cardiovascular disease. Among the persons proceeded for kidney donation cardiovascular problems are an important cause of disqualification.
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