Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Oral Hypoglycemic Agents: α-Glucosidase Inhibitors01:19

Oral Hypoglycemic Agents: α-Glucosidase Inhibitors

909
α-glucosidase inhibitors, including acarbose (Precose), miglitol (Glyset), and voglibose (Voglib) (primarily available in Asia), are drugs that control blood sugar levels by delaying the digestion of starch and disaccharides. They achieve this by inhibiting α-glucosidase enzymes in the intestine, which slow the absorption of carbohydrates in the intestine, which in turn leads to a prolonged release of the glucoregulatory hormone GLP-1 from intestinal L-cells.
Acarbose and miglitol are...
909
Cardiomyopathy VII: Pre and Post Operative Nursing Management01:28

Cardiomyopathy VII: Pre and Post Operative Nursing Management

440
Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...
440
Oral Hypoglycemic Agents: Sulfonylureas01:17

Oral Hypoglycemic Agents: Sulfonylureas

1.7K
Sulfonylureas are oral hypoglycemic agents utilized in treating type 2 diabetes. They are characterized by their unique sulfonylurea chemical structure. The family of sulfonylureas is divided into generations. First-generation sulfonylureas, including tolbutamide (Orinase), chlorpropamide (Diabinese), and tolazamide (Tolinase), trigger insulin release from pancreatic β cells and enhance peripheral tissues' insulin sensitivity. The second-generation members, such as glipizide...
1.7K
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy01:26

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

1.1K
Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
1.1K
Enteral Nutrition I: Orogastric and Nasogastric Feeding01:26

Enteral Nutrition I: Orogastric and Nasogastric Feeding

2.7K
Enteral nutrition delivers nutrients directly to the stomach or small intestine through a tube. This method is appropriate for patients who cannot eat but still have a functioning digestive system. It is also beneficial for individuals with swallowing difficulties, anorexia, malabsorption, or those who have undergone gastrointestinal (GI) surgery.
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
2.7K
Oral Hypoglycemic Agents: Glinides01:06

Oral Hypoglycemic Agents: Glinides

995
Repaglinide (Prandin) and Nateglinide (Starlix), known as glinides, are oral insulin secretagogues that stimulate insulin release from pancreatic β cells by closing the ATP-sensitive potassium channels (KATP channel). Repaglinide controls insulin release from pancreatic β cells by managing potassium efflux. It shares two binding sites with sulfonylureas and also has a unique site, indicating overlapping mechanisms of action. With a rapid onset and a 4-7 hour duration, it effectively...
995

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Insulin resistance and inflammation in open versus minimally invasive surgery for colorectal cancer.

Clinical nutrition ESPEN·2026
Same author

Screening for anal high-grade squamous intraepithelial lesions with flexible endoscopy in high-risk individuals.

Scandinavian journal of gastroenterology·2026
Same author

ERAS-Enhanced Recovery After Surgery: The ERAS Society Story.

World journal of surgery·2026
Same author

Use and implementation of prehabilitation in major abdominal surgery: Results of an international survey.

Clinical nutrition (Edinburgh, Scotland)·2026
Same author

Reversal of Roux-en-Y Gastric Bypass: A Swedish National Cohort Study.

Annals of surgery·2026
Same author

Energy and Micronutrient Intake One Year After Sleeve Gastrectomy Versus Roux-en-Y Gastric Bypass: A Substudy of the Bypass Equipoise Sleeve Trial.

Obesity surgery·2026

Related Experiment Video

Updated: Apr 15, 2026

A Novel Procedure for Evaluating the Reinforcing Properties of Tastants in Laboratory Rats: Operant Intraoral Self-administration
11:16

A Novel Procedure for Evaluating the Reinforcing Properties of Tastants in Laboratory Rats: Operant Intraoral Self-administration

Published on: February 6, 2014

13.3K

Preoperative oral carbohydrate therapy.

Jonas Nygren1, Anders Thorell, Olle Ljungqvist

  • 1aDepartment of Clinical Sciences, Danderyds Hospital, Karolinska Institutet bDepartment of Surgery, Ersta Hospital, Stockholm cDepartment of Surgery, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.

Current Opinion in Anaesthesiology
|April 2, 2015
PubMed
Summary

Preoperative oral carbohydrates (POC) reduce the negative effects of surgical stress. This strategy improves recovery and metabolic response, especially for patients undergoing major surgery.

More Related Videos

Characterization of Metabolic Status in Nonhuman Primates with the Intravenous Glucose Tolerance Test
06:59

Characterization of Metabolic Status in Nonhuman Primates with the Intravenous Glucose Tolerance Test

Published on: November 13, 2016

11.5K
CT-guided Preoperative Localization of Pulmonary Nodules Using a Glucose Test and Tissue Adhesive
02:37

CT-guided Preoperative Localization of Pulmonary Nodules Using a Glucose Test and Tissue Adhesive

Published on: January 30, 2026

122

Related Experiment Videos

Last Updated: Apr 15, 2026

A Novel Procedure for Evaluating the Reinforcing Properties of Tastants in Laboratory Rats: Operant Intraoral Self-administration
11:16

A Novel Procedure for Evaluating the Reinforcing Properties of Tastants in Laboratory Rats: Operant Intraoral Self-administration

Published on: February 6, 2014

13.3K
Characterization of Metabolic Status in Nonhuman Primates with the Intravenous Glucose Tolerance Test
06:59

Characterization of Metabolic Status in Nonhuman Primates with the Intravenous Glucose Tolerance Test

Published on: November 13, 2016

11.5K
CT-guided Preoperative Localization of Pulmonary Nodules Using a Glucose Test and Tissue Adhesive
02:37

CT-guided Preoperative Localization of Pulmonary Nodules Using a Glucose Test and Tissue Adhesive

Published on: January 30, 2026

122

Area of Science:

  • Perioperative Medicine
  • Surgical Stress Response
  • Metabolic Adaptation

Background:

  • Managing the body's response to surgical stress is critical in major surgery.
  • Preoperative oral carbohydrates (POC) are proposed to mitigate these stress-induced derangements.
  • Evidence supports POC as a strategy to improve patient outcomes.

Purpose of the Study:

  • To review the current evidence and rationale for using preoperative oral carbohydrates (POC).
  • To assess the impact of POC on postoperative recovery and metabolic response.
  • To evaluate the clinical outcomes associated with preoperative carbohydrate loading.

Main Methods:

  • Systematic review of existing literature and randomized controlled trials.
  • Analysis of cohort studies in patients undergoing major abdominal surgery.
  • Evaluation of data from Cochrane Collaboration reviews.

Main Results:

  • POC use is associated with enhanced gastrointestinal recovery and shorter hospital stays.
  • Improved postoperative metabolic response includes reduced insulin resistance and protein sparing.
  • POC administration preserves immune function and improves muscle function.

Conclusions:

  • Avoiding preoperative fasting with POC attenuates postoperative insulin resistance and improves metabolic response.
  • POC enhances perioperative well-being and leads to better clinical outcomes.
  • The benefits of POC are most pronounced in patients undergoing major surgical procedures.