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Updated: Apr 15, 2026
Stromal Vascular Fraction-enriched Fat Grafting for the Treatment of Symptomatic End-neuromata
Published on: November 23, 2017
History of fat grafting: from ram fat to stem cells
Riccardo F Mazzola1, Isabella C Mazzola2
1Department of Clinical Sciences and Community Health, Fondazione Ospedale Maggiore Policlinico IRCCS, Via F. Sforza 35, Milano 20122, Italy.
Abstract:
Fat injection empirically started 100 years ago to correct contour deformities mainly on the face and breast. The German surgeon Eugene Hollaender (1867-1932) proposed a cocktail of human and ram fat, to avoid reabsorption. Nowadays, fat injection has evolved, and it ranks among the most popular procedures, for it provides the physician with a range of aesthetic and reconstructive clinical applications with regenerative effects on the surrounding tissues. New research from all over the world has demonstrated the role of adipose-derived stem cells, present in the adipose tissue, in the repair of damaged or missing tissues.
