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Surfactant Depletion Combined with Injurious Ventilation Results in a Reproducible Model of the Acute Respiratory Distress Syndrome ARDS
Published on: April 7, 2021
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The acute respiratory distress syndrome
Ariel M Modrykamien1, Pooja Gupta1
1Division of Pulmonary and Critical Care Medicine, Baylor University Medical Center at Dallas, Dallas, Texas (Modrykamien), and the Division of Pulmonary, Sleep, and Critical Care Medicine, Creighton University Medical Center, Omaha, Nebraska (Gupta).
Proceedings (Baylor University. Medical Center)
|April 2, 2015
Summary
Acute Respiratory Distress Syndrome (ARDS) causes respiratory failure and high mortality. Early recognition and interventions are crucial for managing this severe condition and improving patient outcomes.
Area of Science:
- Critical Care Medicine
- Pulmonology
- Respiratory Medicine
Background:
- Acute Respiratory Distress Syndrome (ARDS) is a significant cause of acute respiratory failure.
- It is associated with high mortality rates and long-term physical and cognitive impairments.
Purpose of the Study:
- To provide updated concepts in ARDS management.
- To discuss the new definition, risk factors, and pathophysiology of ARDS.
- To review current evidence on ventilation, adjunctive therapies, and management of refractory hypoxemia.
Main Methods:
- This is a review article.
- It synthesizes current evidence and updated concepts in ARDS.
Main Results:
- The review covers the new definition of ARDS.
- It details risk factors and pathophysiology.
- It examines current therapeutic strategies including ventilation, adjunctive therapies, and interventions for refractory hypoxemia.
Conclusions:
- Early recognition and prompt application of evidence-based interventions are essential for altering the course of ARDS.
- Updated understanding of ARDS definition, pathophysiology, and management strategies is critical.
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