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Induction of Nephrotic Syndrome in Mice by Retrobulbar Injection of Doxorubicin and Prevention of Volume Retention by Sustained Release Aprotinin
Published on: May 6, 2018
Rhabdomyolysis: pathogenesis, diagnosis, and treatment
Patrick A Torres1, John A Helmstetter1, Adam M Kaye2
1Department of Anesthesiology, Louisiana State University Health Sciences Center, New Orleans, LA.
Background:
Rhabdomyolysis is a complex medical condition involving the rapid dissolution of damaged or injured skeletal muscle.
Methods:
This review focuses on the epidemiology, pathophysiology, causes, presentation, diagnosis, complications, management, and anesthetic considerations related to rhabdomyolysis.
Results:
Any form of muscle damage--and by extension any entity that causes muscle damage--can initiate rhabdomyolysis. One of the most important treatment goals when rhabdomyolysis is suspected is avoiding acute kidney injury.
Conclusion:
All clinicians should be aware of common causes, diagnosis, and treatment options.
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