Related Experiment Video
Updated: Apr 15, 2026
Multicellular Human Alveolar Model Composed of Epithelial Cells and Primary Immune Cells for Hazard Assessment
Published on: May 6, 2020
Hepatitis B immunization in healthcare workers.
Vishal Batra1, Amitava Goswami2, Sunil Dadhich2
1Department of Medicine (Vishal Batra, Dinesh Kothari), Dr Sampurnanand Medical College, Jodhpur, India.
Many healthcare workers (HCWs) remain unvaccinated against hepatitis B virus (HBV). Even vaccinated HCWs may have low anti-HBs titers, necessitating booster doses and screening.
Area of Science:
- Occupational health
- Immunology
- Infectious disease epidemiology
Background:
- Healthcare workers (HCWs) face a high risk of hepatitis B virus (HBV) infection.
- Assessing HBV immunization and anti-HBs titers in HCWs is crucial for occupational safety.
Purpose of the Study:
- To evaluate the hepatitis B virus (HBV) immunization status among healthcare workers (HCWs).
- To determine the anti-hepatitis B surface antibody (anti-HBs) titers in vaccinated HCWs.
Main Methods:
- Prospective examination of anti-HBs titers in 464 enrolled HCWs.
- Comparison of titers based on vaccination timing (within or beyond 5 years) and booster dose status (<1 year vs. >1 year).
Main Results:
- 49.6% of HCWs were vaccinated, with doctors showing the highest vaccination rate (92.5%).
- Among vaccinated HCWs, 59.2% had anti-HBs titers >100 mIU/mL, but 30% had titers <10 mIU/mL.
- Mean anti-HBs titers were significantly lower in those vaccinated >5 years ago and those who received a booster dose >1 year ago.
Conclusions:
- A substantial proportion of HCWs are unvaccinated or have suboptimal anti-HBs titers.
- Routine anti-HBs titer measurement, booster administration, and HBsAg screening should be mandatory for HCWs.
- Ensuring adequate HBV immunity in HCWs is essential to prevent occupational transmission.
More Related Videos
11:36Induction of Drug-Induced, Autoimmune Hepatitis in BALB/c Mice for the Study of Its Pathogenic Mechanisms
Published on: May 29, 2020
10:37Analysis of HBV-Specific CD4 T-cell Responses and Identification of HLA-DR-Restricted CD4 T-Cell Epitopes Based on a Peptide Matrix
Published on: October 20, 2021
Related Concept Videos
01:26Standard Precaution
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
01:25Transmission-based Precautions II: Airborne and Protective Environment
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
01:22Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
01:25Hepatitis
01:17Transmission-based Precautions I: Contact, Enteric, and Droplets
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
01:28Pulmonary Tuberculosis V
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...