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Vitamin D levels in children diagnosed with acute otitis media

Atilla Cayir, Mehmet Ibrahim Turan, Ozalkan Ozkan

    JPMA. the Journal of the Pakistan Medical Association
    |April 3, 2015
    PubMed

    Insights

    Children with acute otitis media had lower serum 25-hydroxy vitamin D levels than healthy controls, suggesting vitamin D deficiency may contribute to this common ear infection.

    Area of Science:

    • Pediatrics
    • Infectious Diseases
    • Endocrinology

    Background:

    • Acute otitis media (AOM) is a common childhood infection.
    • Vitamin D plays a crucial role in immune function.
    • The association between vitamin D deficiency and AOM requires further investigation.

    Purpose of the Study:

    • To examine the relationship between serum 25-hydroxy vitamin D levels and acute otitis media in children.
    • To compare vitamin D status in children with AOM versus healthy controls.

    Main Methods:

    • A randomized, single-blind, case-control study.
    • Involved ambulatory children diagnosed with AOM and healthy controls.
    • Serum 25-hydroxy vitamin D, calcium, and parathormone levels were measured.

    Main Results:

    • Serum 25-hydroxy vitamin D levels were significantly lower in children with AOM (20.6±10.2 ng/mL) compared to controls (23.8±10.3 ng/mL).
    • No significant differences were observed in calcium or parathormone levels between groups.
    • The study included 169 participants (88 cases, 81 controls).

    Conclusions:

    • Vitamin D deficiency is associated with a higher risk of acute otitis media in children.
    • Lower serum 25-hydroxy vitamin D levels in AOM cases suggest a potential role for vitamin D in otitis media pathogenesis.
    • Further research is warranted to explore vitamin D supplementation as a preventive or therapeutic strategy for AOM.
    Abstract

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