Related Experiment Video
Updated: Apr 15, 2026

11:08
Proofreading and DNA Repair Assay Using Single Nucleotide Extension and MALDI-TOF Mass Spectrometry Analysis
Published on: June 19, 2018
10.3K
Plagiarism detection softwares: useful tools for medical writers and editors
JPMA. the Journal of the Pakistan Medical Association
|April 3, 2015
Abstract
No abstract available in PubMed .
Related Concept Videos
Proofreading
62.6K
Overview
62.6K
Proofreading
21.1K
21.1K
Mismatch Repair
45.9K
Overview
45.9K
Replication in Eukaryotes
208.6K
Overview
208.6K
Replication in Prokaryotes
104.5K
Overview
104.5K
Improving Translational Accuracy
15.7K
Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single mismatch to no correct base pairing at all. The free energy difference between the correct and nearly correct base pairs can be as small as 3 kcal/ mol. With complementarity being the only proofreading step, the estimated error frequency would be one wrong amino acid in every 100 amino acids incorporated. However, error frequencies observed in...
15.7K

