Sequence and linkage of the V kappa 21A and G germ-line gene segments in the mouse

The germ-line V gene segments encoding the subgroups A and G of the BALB/c V kappa 21 family were cloned and assigned to the previously described 30-kb cluster of the V kappa 21 family. Sequence comparison revealed close homology between the two gene segments at the DNA and the predicted amino acid sequence level, indicating that V kappa 21A and V kappa 21G originated by a rather recent gene duplication.