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Published on: February 23, 2024
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[Effect of premolar extractions on third molar angulation changes: a meta-analysis]
Linlin Fan1, Qin Kuang, Yujuan Tang
1Department of Orthodontics, Affi liated Hospital of Stomatology, Chongqing Medical University; Chongqing Key Laboratory for Oral Diseases and Biomedical Science, Chongqing 401147, China.
Summary
Premolar extractions significantly alter third molar angulation in orthodontic patients, particularly in the maxilla. Second premolar extraction offers the most improvement for maxillary third molar angulation.
Area of Science:
- Orthodontics
- Dental Surgery
- Maxillofacial Radiology
Background:
- Third molar angulation is a critical factor in orthodontic treatment outcomes.
- The impact of premolar extractions on third molar development remains a subject of investigation.
Purpose of the Study:
- To evaluate the influence of premolar extractions on third molar angulation changes in orthodontic patients.
- To compare the effects of first versus second premolar extraction on mandibular third molar angulation.
Main Methods:
- A systematic literature search was conducted across multiple databases (Cochrane, PubMed, Embase, etc.) from 1990 to 2014.
- Meta-analysis was performed on ten studies involving 712 patients, comparing extraction and control groups.
- The extraction group was subdivided into first and second premolar extraction cohorts.
Main Results:
- Premolar extractions significantly altered third molar angulation in both maxillary and mandibular arches compared to controls (P<0.05).
- Average angulation differences were 5.19° in the maxilla and 3.55° in the mandible.
- No significant difference in mandibular third molar angulation was observed between first and second premolar extraction subgroups (P>0.05).
Conclusions:
- Orthodontic treatment with premolar extractions positively impacts maxillary third molar angulation.
- Second premolar extraction is identified as the optimal choice for improving maxillary third molar angulation.

