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Asymptomatic bacteriuria in normal and high-risk pregnancy
1Department of Obstetrics and Gynecology B, Serlin Maternity Hospital, Tel-Aviv Medical Center, Israel.
European Journal of Obstetrics, Gynecology, and Reproductive Biology
|November 1, 1989
Summary
Asymptomatic bacteriuria in pregnant women significantly increases the risk of developing urinary tract infections (UTIs). Early screening and treatment of asymptomatic bacteriuria are crucial for preventing cystitis and pyelonephritis during pregnancy.
Area of Science:
- Obstetrics and Gynecology
- Infectious Diseases
- Urology
Background:
- Asymptomatic bacteriuria (ASB) is common in pregnancy and linked to adverse outcomes.
- High-risk pregnancies, including diabetes and prior UTIs, show increased ASB incidence.
- Early detection of ASB is vital for preventing complications like cystitis and pyelonephritis.
Purpose of the Study:
- To determine the incidence of ASB in normal and high-risk pregnancies.
- To assess the correlation between ASB and the development of clinical urinary tract infections (UTIs).
- To evaluate the predictive value of early pregnancy urine cultures for later UTI development.
Main Methods:
- Urine cultures were performed on 1130 normal and 211 high-risk pregnant women.
- High-risk groups included 136 diabetics and 75 with a history of UTIs.
- Statistical analysis was used to compare ASB incidence and UTI development.
Main Results:
- ASB prevalence was 5.9% in normal, 12.5% in diabetic, and 18.5% in prior UTI groups.
- A significant association (p < 0.001) was found between ASB and clinical UTIs across all groups.
- ASB was present in 33.3% of normal pregnancies with cystitis and 66% with pyelonephritis.
Conclusions:
- ASB is a significant risk factor for developing symptomatic UTIs in pregnant women.
- Negative early pregnancy urine cultures correlate with the absence of later UTIs.
- Screening for ASB in all pregnancies, especially high-risk ones, is recommended for prevention.