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Related Concept Videos

Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

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Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
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Tumor Immunotherapy01:27

Tumor Immunotherapy

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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Gene Therapy00:59

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Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be...
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Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

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Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
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Tissue Transplantation01:24

Tissue Transplantation

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Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
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Related Experiment Video

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Automated Cell Enrichment of Cytomegalovirus-specific T cells for Clinical Applications using the Cytokine-capture System
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Cell therapy worldwide: an incipient revolution.

Mahendra Rao1, Chris Mason, Susan Solomon

  • 1New York Stem Cell Foundation, 3969 Broadway 4th floor, NYC, NY 10032, USA.

Regenerative Medicine
|April 4, 2015
PubMed
Summary

Regenerative medicine is a dynamic global field. Despite infrastructure challenges, advancements in cell therapies have led to successful treatments for thousands of patients worldwide.

Keywords:
compositescosmeceuticalsinduced pluripotent stem cellsmedical tourismmesenchymal stem cellsneural stem cellsregenerative medicinetherapytissuetransplant

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Area of Science:

  • Regenerative Medicine
  • Cell Therapy
  • Tissue Engineering

Background:

  • The field of regenerative medicine is globally active and diverse.
  • Pioneering work has identified successful and unsuccessful business and product models.
  • The sector faces challenges including evolving regulations, funding, and infrastructure limitations.

Purpose of the Study:

  • To provide an overview of the current state of the regenerative medicine field.
  • To highlight the evolution from stem cell therapies and transplants to diverse cell-based products.
  • To underscore the growing number of patients treated with cell therapies.

Main Methods:

  • Review of organizational and product models in regenerative medicine.
  • Analysis of regulatory and funding landscapes.
  • Assessment of technological advancements and their impact.
  • Examination of the transition from stem cell therapy and organ transplantation.

Main Results:

  • Regenerative medicine encompasses diverse products from multiple cell sources.
  • Numerous cell therapies have gained regulatory approval in various countries.
  • Tens of thousands of patients have benefited from cell therapy treatments.
  • The field is characterized by flux due to regulatory, funding, and technological changes.

Conclusions:

  • Regenerative medicine has evolved significantly, offering viable therapeutic options.
  • Despite challenges, the field demonstrates substantial growth and patient impact.
  • Continued innovation and investment are crucial for future advancements.