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German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with...
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The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
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Evaluation of partial coherence correction in X-ray ptychography.

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    This study analyzes partial coherence correction in X-ray ptychography. Results show correction effectiveness depends on coherence, probe, and sample complexity, guiding experimental strategies for improved imaging.

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    Area of Science:

    • X-ray optics
    • Coherent X-ray Diffraction Imaging (CDI)
    • Ptychography

    Background:

    • Coherent X-ray Diffraction Imaging (CDI) and X-ray ptychography require high X-ray spatial coherence for quality reconstructions.
    • Synchrotron sources often have limited partial coherence, reducing data quality and speckle contrast.
    • The trade-off between X-ray source coherence and flux density for weak scattering materials remains an open question.

    Purpose of the Study:

    • To systematically analyze the effectiveness of partial coherence correction in ptychography.
    • To investigate the influence of illumination coherence, probe complexity, and sample complexity on correction effectiveness.
    • To assess the ability of ptychographic algorithms to refine unknown probe and coherence functions during reconstruction.

    Main Methods:

    • Simulated noise-free data for ptychographic reconstructions.
    • Analysis of partial coherence correction effectiveness across varying coherence properties.
    • Evaluation of algorithm performance with diverse illumination and sample phase complexities.

    Main Results:

    • Partial coherence correction effectiveness is dependent on the interplay between illumination coherence, probe phase diversity, and sample phase complexity.
    • Ptychographic algorithms demonstrate capability in refining unknown probe and complex coherence functions.
    • The study provides a framework for optimizing experimental parameters in ptychography.

    Conclusions:

    • Partial coherence correction is a viable strategy in ptychography, but its effectiveness is nuanced.
    • Understanding the relationship between coherence, probe, and sample is crucial for successful X-ray imaging.
    • Ptychography algorithms offer robust solutions for handling partial coherence and refining illumination parameters.