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Giant Cervico-mediastinal Well-differentiated Liposarcoma.
Ottavio Rena1, Fabio Davoli1, Francesco Pia2
1Thoracic Surgery Unit, University of Eastern Piedmont, Azienda Ospedaliero-Universitaria "Maggiore della Carità", Novara, Italy.
Heart, Lung & Circulation
|April 4, 2015
Summary
We present a rare case of a giant, encapsulated low-grade liposarcoma in the neck and mediastinum. Surgical resection was successful, with the patient remaining disease-free at 24 months.
Area of Science:
- Oncology
- Surgical Pathology
- Thoracic Surgery
Background:
- Liposarcomas are rare soft tissue tumors.
- Neck and mediastinal liposarcomas are exceptionally uncommon.
Observation:
- A 58-year-old male presented with dysphonia, dysphagia, dyspnea, and cough.
- Imaging revealed a giant mass in the deep cervical space at C6, extending into the posterior mediastinum.
- The mass caused vocal cord palsy and significant displacement of the trachea and esophagus.
Findings:
- Complete surgical resection was achieved via a combined cervical and thoracic approach.
- A tracheostomy was necessary due to the risk of recurrent laryngeal nerve dysfunction.
- Histopathological diagnosis confirmed an encapsulated low-grade liposarcoma.
Implications:
- This case highlights the possibility of rare liposarcoma presentations in the neck and mediastinum.
- Multidisciplinary surgical management is crucial for successful outcomes.
- Complete resection offers a favorable prognosis for low-grade liposarcomas in this location.

